Mesothelioma
Summary
Mesothelioma is a rare
cancer, but the number of people it affects is increasing.
There are over 2,000 new cases in the UK each year. It is
much more common in men than in women.
These
figures are even greater in the US.
Mesothelioma occurs in the
pleura (the membranes surrounding the lungs) or, more
rarely, in the peritoneum (the membrane lining the abdomen).
The cancer tends to spread locally. It is often quite
advanced at the time of diagnosis.
Mesothelioma attorneys
and Mesothelioma lawyers are
having increasing claims being taken against various
companies who used to deal with asbestos, or for employees
who used to work in an asbestos environment.
Risk factors
- Asbestos
Exposure to asbestos is the main risk factor for
mesothelioma. Around 8 out of 10 people with mesothelioma
have been exposed to asbestos. It can take fifteen to
forty years following asbestos exposure for mesothelioma
to develop.
Changes in the pleura
occur when people breathe in asbestos fibres. These may
penetrate the lining of the lung. Mesothelioma of the
abdominal lining may result from coughing up and
swallowing inhaled asbestos fibres.
In the past, asbestos
was used widely in the building industry, the ship
building industry and in the manufacture of household
appliances. It is an effective insulating material because
it does not conduct heat well and is resistant to melting
or burning.
Family members of people
exposed to asbestos also run a higher risk of developing
mesothelioma. This is because workers can carry asbestos
fibres into the home on their clothes.
Many people who develop
mesothelioma because of exposure to asbestos may be
eligible for compensation. They should discuss this with
their doctor.
- Other chemicals
A naturally occurring mineral called zeolite, which is
found in Turkey, may cause some cases of mesothelioma.
- Radiation
Mesothelioma may develop following exposure to radiation
from a substance called thorium dioxide, which was used to
create X-rays of blood vessels until 1955.
- Other lung diseases
Mesothelioma is more common in people who have had serious
lung diseases such as tuberculosis.
Prevention
Thanks to very strict
regulations on asbestos, the main cause of mesothelioma, it
is likely that this type of cancer will become increasingly
rare. For now, the number of cases is still increasing
because of the delay between exposure to asbestos and the
development of the disease. People whose work involves
demolition of old buildings and structures should make sure
that proper health and safety measures are in place.
Screening
People who may have been
exposed to asbestos at work should ask their doctor about
the possibility of regular check-ups, which usually includes
an annual X-ray.
Signs and symptoms
Mesothelioma does not
generally cause symptoms in the early stages. Symptoms of
mesothelioma in the lining of the lung can include:
- pain in the lower back
or the side of the chest
- a persistent cough
- shortness of breath
- hoarseness (a 'husky'
voice)
- unexplained weight loss
- sweating
- difficulty swallowing.
Symptoms of mesothelioma
in the abdominal lining may include:
- abdominal pain
- swelling in the abdomen
- nausea and vomiting
- loss of appetite
- unexplained weight loss
- change in bowel habits
These signs and symptoms
usually indicate problems other than cancer. However, people
who have been exposed to asbestos or notice any symptoms
should see their doctor.
Detection
Initially the doctor will
ask questions about medical history, and carry out a
physical examination. The doctor or, after referral, a
specialist may want to do further tests, which can include :
- Fluid drainage
Many people with mesothelioma have fluid around their
lungs or in their abdominal cavity. The test uses a needle
to extract this fluid. A specialist can then analyse it in
the laboratory to see if any cancer cells are present.
- Thoracoscopy
Since mesothelioma can
affect the lungs and the abdomen, doctors may also carry out
some of the tests commonly used to detect lung or stomach
cancer, such as:
- Chest X-ray or
abdominal X-ray
- CT scan
- Bronchoscopy
- Mediastinoscopy
- Laparoscopy
Treatment
Possible treatments
include:
Surgery
If the cancer is in its early stages, doctors may be able to
remove it surgically. The doctors might also use surgery to
relieve symptoms such as pain and the accumulation of fluid.
Radiotherapy
Doctors usually use radiotherapy to control symptoms such as
fluid collection or pain.
Chemotherapy
Doctors may use chemotherapy after surgery or on its own.
They can also use it to relieve symptoms caused by the
cancer, such as pain.
Supportive care
Some people may be too ill to tolerate intense chemotherapy,
radiotherapy, or surgery. Supportive treatment will aim to
control and manage some of the effects and symptoms that the
cancer causes, such as pain, breathing problems, weight loss
and other symptoms.
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